Spectral Imaging of the Retinal Blood Oxygen Saturation

Jim Beach; Associate Professor Adjunct, Department of Ophthalmology, Louisiana State University, New Orleans

28th July, 2010 at 1.00 pm - EM1.27

Joint UoE/HWU videoconference seminar

This seminar will present one- and two-dimensional hyperspectral methods for imaging the blood oxygen saturation in retinal blood vessels. Results of a hyperspectral study of altered oxygen delivery in experimental glaucoma show that oxygenation of the central region of the optic disc is preserved during high intraocular pressure. A diffusion model based on saturation changes at elevated pressure shows evidence that oxygen content of the blood flow into the retina is flow-dependent. Two-wavelength multi-spectral methods for determining retinal blood oxygen saturation in human subjects are described, along with recent results from glaucoma patients using a commercially available retinal oximeter.